The following 2019 Bridging Collaborative agenda will focus on providing collaborative opportunities with panel discussions stimulated through keynote and pillar presentations. In addition, there will be roundtable luncheon discussions on a variety of topics. You will receive an opportunity in February to sign up for your preferred luncheon discussion groups.

Please ensure you are registered in advance so you are on the National Academy of Sciences attendee roster. License ID will be required upon registration check in for security purposes.

Monday, March 4 (Day One)

Registration and Breakfast
9 – 10 a.m.

Session One

10 – 11 a.m.

Welcome and Opening Remarks

Program Co-Chairs and Collaborative Founders

Keynote:
What is the Learning Health Community? What is an Learning Health System? What Would a Well-Functioning LHS Mean to Patients?

Joshua Rubin, Learning Health Community
John Barry, Pharm-Olam

Session Two

Session Chair: Kurt Mussina, Frenova

11 a.m. – 12:30 p.m.

Pillar Presentations:
Perceptions and Attitudes of Patients as Partners in Research: A Survey

Lindsey Wahlstrom-Edwards, Antidote
Anne-Marie Hess, SCORR Marketing

Aligning Direct-to Patient Trials With Patient Advocacy Groups: Putting Patient-Centricity Into Practice

Michael Keens, Firma Clinical Research

Patients at the Center of Research and Health Care: An Industry Survey

Lisa Henderson, Applied Clinical Trials

Panel Discussion:
The Bridging Collaborative and Learning Health Systems: What Could These Mean for Patients?

Facilitator: Kurt Mussina, Frenova Renal Research
Anne-Marie Hess, SCORR Marketing
Lisa Henderson, Applied Clinical Trials
Michael Keens, Firma Clinical Research
Lindsey Wahlstrom-Edwards, Antidote
Ivor Clarke, SubjectWell
Derek Ansel, PRA Health Sciences
Stephen Chick, Veradigm Health
Joanne Stone Wyman, Patient

Lunch
12:30 – 2 p.m.

Ten roundtable discussion groups with 10 different topics led by 10 experts (10 participants per table) will meet during this time for those who are interested in participating.

Day One Luncheon Discussion Group Topics and Leaders

Using Behavioral Science to Motivate Patients and Stakeholders

Dr. Kathleen Starr, Syneos Health

Engaging Patients and Caregivers as Partners

Lindsey Wahlstrom-Edwards, Antidote, and Anne-Marie Hess, SCORR Marketing

The Future of the Case Report Form (CRF) Part 1

Shannon Labout, SCDM Board Chair 2018

New Paths for global Disease-Specific Standards

Rebecca Kush, Elligo Health Research with FDA Representatives

Shifting the Clinical Trials Paradigm from Approving Drugs to Curing Patients

Dr. Marty Tenenbaum, Cancer Commons

Knowledge into Practice: Realizing the Benefit of Learning Health Systems

Meghan Klopchin or Graham Millar, Eli Lilly

Data Science: Working with Real World Data

Dr. Michael Ibara, Elligo Health Research

Preventing ‘Last Mile Privatization’ of Life-Saving Knowledge

Joshua Rubin, Learning Health Community

Session Three

Session Chair: Amy Nordo, Pfizer

3 – 3:30 p.m.

Pillar Presentations:
Development of a New Seamless Data Stream from EMR to EDC System using SS-MIX2 Standards Applied for Observational Research in Diabetes Mellitus

Professor Hiroshi Watanabe, Hamamatsu University School of Medicine

The ROAD2Health Initiative and TRANSFoRm Project (Europe, Serbia, China)

Professor Brendan Delaney, Imperial Collage

Re-Thinking Clinical Research Data from Rare Diseases to Precision Medicine

Alex Sherman, Massachusetts General Hospital, Harvard

Panel Discussion:
Addressing Global Challenges to Bridging the Gap and Realizing Learning Health Systems

Facilitator: Amy Nordo, Pfizer
Professor Hiroshi Watanabe, Hamamatsu University School of Medicine
Professor Brendan Delaney, Imperial Collage
Alex Sherman, Massachusetts General Hospital
Dr. Kimura, Hamamatsu University School of Medicine
Eric Gildenhuys, Deep 6 A

Break
3:30 – 4 p.m.

Session Four

4 – 5 p.m.

Pillar Presentation:
FDA End-to-End Standards Strategy to Bridging Research and Health Care

Dr. Ron Fitzmartin, FDA/CBER
One additional FDA representative

Session Five

5 – 6 p.m.

Panel Discussion:
Reinventing Clinical Research and Cancer Care

Facilitator: Marty Tenenbaum
Dr. Brian Alexander, Dana Farber Cancer Institute
Dr. Sean Khozin, FDA Cancer Center of Excellence

Networking Reception
6 – 7 p.m.
National Academy of Sciences Atrium

Tuesday, March 5 (Day Two)

Breakfast & Registration
7:30 – 8:20 a.m.

Session Six

8:20 – 9:20 a.m.

Opening Remarks

Program Co-Chairs and Collaborative Founders

Keynote:
Innovations Towards Collaboratively Bridging Clinical Research and Clinical Care

Badhri Srinivasan, Novartis

Keynote:
Dynamic Assembly: Synthesizing Data for Deeper Patient Behavioral Learnings and Insights

Michelle Keefe, Syneos Health

Session Seven

9:20 – 10:30 a.m.

Pillar Presentations:
New Ways to do Clinical Trials: Opportunities to Solve Big Hairy Problems

Brian Burk, Verizon

New Clinical Research Models Addressing the Industry’s Core Challenges

Dr. Michael Gibertini, Elligo Health Research

Panel Discussion:
Reinventing Research – Thoughts from Various Stakeholders

Facilitators: Brian Burk and Dr. Michael Gibertini
Dr.Nancy Nurthen, Digital Infuzion
Kimberly Finn, Marken
Dr. Mary Tobin, ACRES
Solomon Babani, PRA Health Sciences
Blake Adams, Florence Healthcare
Joe Dustin, Medidata Solutions

Break
10:30 – 11 a.m.

Session Eight

11 a.m. – 12:30 p.m.

Pillar Presentations:
Quality Real-World Data for Regulatory Use – From Raw Data to Fit-for-Purpose

Dr. Paul Bleicher, Optum Labs

Delivering Timely and Credible Real-World Evidence; Overcoming Regulatory, Legal and Logistical Challenges for the Benefit of Patients

Brande Ellis Yaist, Eli Lilly

Panel Discussion:
Designing Quality and Real-World Evidence into Research Studies and Learning Health Systems from the Beginning

Facilitator: TBD
Dr. Michio Kimura, Hamamatsu Hospital
Dr. Bleicher, Optum Labs
Brande Ellis Yaist, Eli Lilly
Dr. Lauren Becnel, Pfizer
David Thompson, Syneos Health
Dr. Hugh Levaux, Protocol First

Lunch
12:30 – 2 p.m.

Ten roundtable discussion groups with 10 different topics led by 10 experts (10 participants per table) will meet during this time for those who are interested in participating.

Day Two Luncheon Discussion Group Topics and Leaders

Solving the Interoperability Challenge

Dr. Michio Kimura, Hamamatsu Hospital and Dr. Hugh Levaux, Protocol First

NIH/NCATS Center for Data 2 Health (CD2H)

Dr. Melissa Haendel, OHSU and Dr. Sam Volchenboum, University of Chicago Clinical Research Informatics

The Future of eSource Technology

Amy Nordo, Pfizer and SCDM eSource Consortium Representative

The Future of the Case Report Forum Part 2

Shannon Labout, SCDM 2018 Board Chair

Integrated Research Organizations and Site Perspectives of Research

Chad Moore, Elligo Health Research

The Future of the Learning Health Community: Taking the Consensus Action Plan Forward to Realize Learning Health Systems

Dr. Jonathan Silverstein, University of Pittsburgh and LHC Board Chair

Collaborative Models for Data Sharing

Adam Pertman, Stewards of Change

Session Nine

2 – 3 p.m.

Panel Discussion:
Unlocking Real-World Value for EHRs: Harmonization of Common Data Models for Real-World Evidence with Oncology Use Case

Facilitator: Dr. Ken Gersing, NIH/NCATS and Scott Gordon, FDA
Mitra Rocca, FDA
David Vulcano, Hospital Corporation of America
Dr. Sam Volchenboum, University of Chicago Clinical Research Informatics
Dr. Shrujal Baxi, Flatiron
Christian Reich, OMOP/IQVIA
Dr. Michael Ibara, Elligo Health Research

Session Ten

3 – 4:20 p.m.

Pillar Presentations:
Creating Learning Health Systems Through Structured, Digitized Care Plan Information from EHRs

Dr. Hidehisa Soejima, Saiseikai Kumamoto Hospital

Bridging Partnership Between the Department of Veteran Affairs and Industry for High-Quality Clinical Trials

Dr. Rick Starrs, NAVREF
Dr. Grant D. Huang, Veteran Association

Panel Discussion:
Next Steps to Bridge the Chasm

Facilitators: Rebecca Kush, Elligo Health Research and Joshua Rubin, Learning Health Community
Dr. Rick Starrs, NAVREF
Dr. Grant Huang, Veterans Association
Dr. Hidehise Soejima, Saiseikai Kumamoto Hospital
Blake Adams, Florence Healthcare
Dr. Kathleen Starr, Syneos Health

Closing Remarks
4:20 – 4:30 p.m.